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PSMD11 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550566

Catalog No. PA550566


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Description

Description

The antibody detects endogenous levels of total PSMD11 protein.

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator.
Specifications

Specifications

PSMD11
Polyclonal
Unconjugated
PSMD11
Liquid
PSMD11
Synthetic peptide corresponding to a region derived from internal residues of human proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Western Blot
2.5 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
O00231, Q8BG32, F1LMZ8
S9, Rpn6, p44.5
Rabbit
IgG
100 μL
-20°C
Primary
303353, 5717, 69077
Documents
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