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PSMD2 Mouse anti-Canine, Human, Mouse, Rat, Clone: OTI1G8, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA503270

Catalog No. 50-167-4208


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Description

Description

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1.
Specifications

Specifications

PSMD2
Monoclonal
0.58 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q13200, Q4FZT9, Q8VDM4
P97, RPN1, S2, TRAP2
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
21762, 287984, 478654, 5708
Immunocytochemistry, Immunofluorescence, Western Blot
OTI1G8
Unconjugated
PSMD2
Liquid
PSMD2
Full length human recombit protein of human PSMD2 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Canine, Human, Mouse, Rat
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