PSRC1 Mouse anti-Human, Clone: GT982, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527857
Positive Control: human PSRC1-transfected 293T cells Predicted Reactivity: Rhesus Monkey (95%), Bovine (86%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.PSRC1 is required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A and ANKRD53 to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression.
|PBS with no preservative|
|Recombit protein encompassing a sequence within the center region of human PSRC1. The exact sequence is proprietary.|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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