Invitrogen™ PSRC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578606

Catalog No. PIPA578606

Description

Positive Control: 293T, A431, human PSRC1-transfected 293T Predicted Reactivity: Rhesus Monkey (95%), Bovine (86%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PSRC1 is required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A and ANKRD53 to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression.

Specifications

• Antigen: PSRC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PSRC1
• Gene Alias: 5430413I02Rik; AL033312; Dda3; differential display and activated by p53; FP3214; MGC1780; OTTHUMP00000013785; OTTHUMP00000013786; p53-regulated DDA3; proline and serine rich coiled-coil 1; proline/serine-rich coiled-coil 1; proline/serine-rich coiled-coil protein 1; Psrc1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56742, 84722
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.86 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q6PGN9, Q9D0P7
• Gene Symbols: PSRC1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human PSRC1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov