Tocris™ PTC 209

Bmi-1 inhibitor; antitumor

Manufacturer: Tocris™ 5191/10

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Catalog No. 51-911-0

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    Inhibitors PTC 209
    Purity >98
    Molecular Weight 495.19
    Quantity 10mg
    Product Type PTC 209

    Bmi-1 inhibitor (IC50 ~ 0.5µM); irreversibly impairs colorectal cancer-initiating cell (CIC) growth. Reduces tumor growth in CIC xenograft assays and results in reduced potential of colorectal cancer cells to initiate tumors in vivo.

    • Chemical Name: N-(2,6-Dibromo-4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)-2-thiazolamine
    • Formula: C17H13Br2N5OS
    • CAS Number: 315704-66-6
    • Solubility: Soluble to 100mM in DMSO and to 20mM in ethanol
    • Purity: >98

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