PTEN/MMAC1 Ab-4 Mouse Monoclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ PTEN/MMAC1 Ab-4, Mouse Monoclonal Antibody.

Supplier:  Epredia MS1601S1

Catalog No. MS1601S1

Description

PTEN/MMAC1, a tumor suppressor, has been implicated in a large number of human tumors and is conserved from humans to worms. Characterization of PTEN protein showed that it is a phosphatase that acts on proteins and on 3-phosphorylated phosphoinositides, and can therefore modulate signal-transduction pathways that involve lipid second messengers. Recent results indicate that at least part of its role is to regulate the activity of the serine/threonine kinase AKT/PKB, and thus influence cell survival signaling.

Host Species: Mouse

Clone: 17.A

Isotype: IgM/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant human PTEN protein

Molecular Weight: 60kDa

Cellular Localization: Cytoplasmic

Recommended for:

• Immunohistochemistry

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: PTEN/MMAC1 Ab-4
• Classification: Monoclonal
• Conjugate: Unconjugated
• Immunogen: Recombinant human PTEN protein
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated

• Applications: Immunohistochemistry (Paraffin)
• Clone: 17.A
• Host Species: Mouse
• Quantity: 500 μL
• Research Discipline: Cancer and Tumor Biology
• Target Species: Human
• Isotype: IgM κ