Invitrogen™ PTF1A Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518733

Catalog No. PIPA518733

Description

This antibody is predicted to react with canine, rat and zebrafish based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.

PFT1A is a component of the pancreas transcription factor 1 complex and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers.

Specifications

• Antigen: PTF1A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PTF1A
• Gene Alias: bHLH transcription factor; bHLH transcription factor p48; BHLHA29; class A basic helix-loop-helix protein 29; class II bHLH protein PTF1A; exocrine pancreas-specific transcription factor p48; p48 DNA-binding subunit of transcription factor PTF1; PACA; PAGEN2; pancreas associated transcription factor 1a; pancreas specific transcription factor, 1a; pancreas transcription factor 1 subunit alpha; pancreas transcription factor1 p48 subunit; pancreas-specific transcription factor 1a; PTF1; PTF1A; PTF1p48; PTF1-p48; Ptfa; si:zc142h2.2; zgc:112216
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 19213, 256297
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q7RTS3, Q9QX98
• Gene Symbols: PTF1A
• Immunogen: Synthetic peptide sequence (WTDEKQLKEQN) corresponding to the internal amino acids of PTF1A (aa 283-293).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG