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PTH Mouse anti-Human, Alexa Fluor™ 532, Clone: 3H9, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP254320AF532

Catalog No. NP24320A32


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Description

Description

PTH Monoclonal antibody specifically detects PTH in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin).
Specifications

Specifications

PTH
3H9
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Conjugated, Purified
PTH
Synthetic peptide corresponding to amino acids 1 to 34 of mature PTH conjugated to a carrier
Protein A or G purified
Apoptosis, Biologically Active Proteins, Cancer
Primary
5741.0
Human
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin)
Alexa Fluor™ 532
50 mM sodium borate with 0.05% sodium azide
Parathormone, Parathyrin, parathyroid hormone, parathyroid hormone 1, PTH1
Mouse
IgG2b Kappa
0.1 mL
Store at 4°C in the dark.
Monoclonal
Epitope of this MAb maps in between aa 1-34. PTH is a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
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