PTH Mouse anti-Human, Alexa Fluor™ 594, Clone: 3H9, Novus Biologicals™
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP254320AF594
DescriptionPTH Monoclonal antibody specifically detects PTH in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin).
|Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin|
|Synthetic peptide corresponding to amino acids 1 to 34 of mature PTH conjugated to a carrier|
|Protein A or G purified|
|Apoptosis, Biologically Active Proteins, Cancer|
|Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)|
|Alexa Fluor 594|
|50 mM sodium borate with 0.05% sodium azide|
|Parathormone, Parathyrin, parathyroid hormone, parathyroid hormone 1, PTH1|
|Store at 4°C in the dark.|
|Epitope of this MAb maps in between aa 1-34. PTH is a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.|
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