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PTH Mouse anti-Human, Clone-SPM604, Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP254434100UG
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DescriptionPTH Monoclonal specifically detects PTH in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
|Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, CyTOF-ready|
|Parathormone, Parathyrin, parathyroid hormone, parathyroid hormone 1, PTH1|
|Apoptosis, Biologically Active Proteins, Cancer|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF|
|PBS with No Preservative|
|A synthetic peptide from the N-terminal of human PTH polypeptide.|
|Protein A or G purified|
|Epitope of this MAb maps in the N-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.|
|Store at -20 to -80C. Avoid freeze-thaw cycles.|
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