PTH Mouse anti-Human, PE/Cy5.5, Clone: SPM604, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP254434PECY55
DescriptionPTH Monoclonal antibody specifically detects PTH in Human samples. It is validated for Flow Cytometry.
|A synthetic peptide from the N-terminal of human PTH polypeptide.|
|Protein A or G purified|
|Apoptosis, Biologically Active Proteins, Cancer|
|PBS with 0.05% Sodium Azide|
|Parathormone, Parathyrin, parathyroid hormone, parathyroid hormone 1, PTH1|
|Store at 4°C in the dark. Do not freeze.|
|Epitope of this MAb maps in the N-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok