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PTK7 Mouse anti-Human, Clone: OTI2E7, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525774

Catalog No. PIMA525774


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Description

Description

Protein-tyrosine kinases (PTKs) play important roles in regulating cell proliferation and differentiation during development. One member of the PTK family, PTK7, has been suggested to regulate the planar cell polarity (PCP) pathway in vertebrates and may play a role in neural convergent extension and neural tube closure. PTK7 has also been implicated in the development of cancer. Loss of PTK7 expression was seen in several melanoma cell lines and biopsies. Conversely, high-throughput analysis of acute myeloid leukemia samples showed an increased level of PTK7 expression compared to normal bone marrow and purified CD34+ cells. Multiple isoforms of PTK7 are known to exist.
Specifications

Specifications

PTK7
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q13308
CCK4; CCK-4; colon carcinoma kinase 4; colon carcinoma kinase-4; inactive tyrosine-protein kinase 7; protein-tyrosine kinase 7; pseudo tyrosine kinase receptor 7; tyrosine-protein kinase-like 7
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
5754
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
OTI2E7
Unconjugated
PTK7
Liquid
PTK7
Full length human recombit protein of PTK7 produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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