Invitrogen™ PTPLAD1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5113839

Catalog No. PIPA5113839

Description

Immunogen sequence: WLDESDAEME LRAKEEERLN KLRLESEGSP ETLTNLRKGY LFMYNLVQFL For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%.

Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May be involved in Rac1-signaling pathways leading to the modulation of gene expression. Promotes insulin receptor/INSR autophosphorylation and is involved in INSR internalization (PubMed:25687571).

Specifications

• Antigen: PTPLAD1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HACD3
• Gene Alias: 3-hydroxyacyl-CoA dehydratase 3; BIND1; B-ind1; Butyrate-induced protein 1; butyrate-induced transcript 1; HACD3; HSPC121; protein tyrosine phosphatase-like A domain containing 1; protein tyrosine phosphatase-like protein PTPLAD1; protein-tyrosine phosphatase-like A domain-containing protein 1; PTPLAD1; very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 3; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51495
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9P035
• Gene Symbols: HACD3
• Immunogen: Synthetic peptide directed towards the N terminal region of human PTPLAD1 (aa 110-159).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov