Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

PTPRC Mouse anti-Human, Biotin, Clone: 4AA9, Abnova™

Mouse monoclonal antibody raised against human PTPRC.

Manufacturer:  Abnova Corporation MAB12408

Catalog No. 89-934-817


Add to cart

Description

Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq]

Specifications

Specifications

PTPRC
4AA9
Mouse monoclonal antibody raised against human PTPRC.
In PBS, pH 7.4 (0.09% sodium azide, 0.2% BSA)
B220/CD45/CD45R/GP180/LCA/LY5/T200
Mouse
IgG2a
50 Reactions
Store at 4°C. Do not freeze.
Monoclonal
Human
Flow Cytometry, Immunofluorescence
Biotin
Flow cytometry Immunofluorescence The optimal working dilution should be determined by the end user.
Liquid
PTPRC
PTPRC
Protein A/G affinity chromatography
RUO
Primary
5788
SDS
Documents
Product Certifications
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit