PTPRE Monoclonal Antibody (OTI4B2), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA501028

Catalog No. 50-167-2170

Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.

Specifications

• Antigen: PTPRE
• Classification: Monoclonal
• Concentration: 0.89 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P23469
• Gene Symbols: PTPRE
• Immunogen: Full length human recombit protein of human PTPRE produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI4B2
• Conjugate: Unconjugated
• Gene: PTPRE
• Gene Alias: HPTPE, PTPE, R-PTP-EPSILON
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5791
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid