PTX3 Mouse anti-Mouse, Clone: 6B11, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA533377
Product is supplied at 1 mL (100 μL/mL). Application Notes: Western blot - A reduced sample treatment and SDS-Page was used. Positive control: Section of inflamed tissues; Negative control: Section of normal tissues.Pentraxins are a protein superfamily that is characterized by a cyclic multimeric structure. Ptx3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that has a non-redundant role in resistance to selected microbial agents. Ptx3 belongs to the family of "long pentraxins", which have C-terminal pentraxin domains and novel amino-terminal domains. Ptx3 binds selected pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa and Salmonella typhimurium. It is synthesized in IgA glomerulonephritis and activates mesangial cells. Secretion of Ptx3 in adipose cells can be induced by TNF . Ptx3 is also involved in amplification of inflammatory reactions and regulation of innate immunity. The human PTX3 gene maps to chromosome 3q25.
|PBS with 0.1% BSA and no preservative|
|Pentraxin-related protein PTX3, Pentaxin-related protein PTX3, Tumor necrosis factor alpha-induced protein 5, TNF alpha-induced protein 5, Tumor necrosis factor-inducible gene 14 protein, TSG-14, TNFAIP5, TSG14, PTX3|
|ELISA, Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Western Blot|
|Recombit mouse PTX3|