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PUF60 Mouse anti-Human, Mouse, Rat, Clone: GT3510, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527821

Catalog No. PIMA527821



Description

Description

Positive Control: mouse brain, rat brain, 293T, A431, HeLa, HepG2 Predicted Reactivity: Chicken (94%), Bovine (96%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

PUF60 encodes a protein that is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.
Specifications

Specifications

PUF60
Monoclonal
0.1 mg/ml
PBS with no preservative
Q3UEB3, Q9UHX1, Q9WV25
SIAHBP1, FIR, poly-U binding splicing factor 60KDa, RoBPI
Mouse
IgG1
100 μl
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
22827, 67959, 84401
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
GT3510
Unconjugated
PUF60
Liquid
PUF60
Recombit protein encompassing a sequence within the center region of human PUF60. The exact sequence is proprietary.
Protein G
RUO
Antibody
Monoclonal
Human, Mouse, Rat
Documents
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