Puromycin, 10 mg/mL in distilled water, sterile-filtered, Alfa Aesar™
Puromycin is also used as a substrate of Mdr-1. It is been widely used in cell culture applications. It also induces apoptosis which was found as parallel apoptosis caused by deprivation of neuronal growth factor (NGF) in developing chick sympathetic neurons; however, this apoptotic activity can be inhibited by several transcriptional inhibitors such as: actinomycin D and α-amanitin (sc-202440) which has lead researchers to hypothesize that apoptosis is triggered through the transcription of particular genes. Shown to arrest cells in G2/M phase. Puromycin is an inhibitor of CD13 and DPP7.
Soluble in water (50 mg/ml at 20°C).
Research Use only: Not intended for animal or human diagnostic or therapeutic use. Optimal working concentration of puromycin varies between cell lines. Usually, the working concentration for eukaryote cell culture is 1-10 µg/ml
|Concentration||10mg/mL in distilled water|
|Quantity||5 x 1mL|
|Chemical Name or Material||Puromycin, sterile-filtered|
GHS H Statement
Harmful if swallowed.
GHS P Statement
Wash thoroughly after handling.
Do not eat, drink or smoke when using this product.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth.
Dispose of contents/container in accordance with local/regional/national/international regulations.
RTECSNumber : AU7350000
storageNote1 : −30° to −10°C