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PXR Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 156071AP

Catalog No. 50-173-0346


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Description

Description

This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.
Specifications

Specifications

PXR
0.19 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O54915, O75469, Q9R1A7
BXR, NR1I2, ONR1, Orphan nuclear receptor PAR1, Orphan nuclear receptor PXR, PAR, PAR1, PAR2, PARq, Prege X receptor, PRR, PXR, SAR, SXR
Rabbit
IgG
150 μL
-20°C
Primary
18171, 84385, 8856
Immunoprecipitation, Western Blot
Unconjugated
NR1I2
Liquid
Nr1i2
PXR Fusion Protein Ag7991
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Documents
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