PXR Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 156071AP
DescriptionThis gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|O54915, O75469, Q9R1A7|
|BXR, NR1I2, ONR1, Orphan nuclear receptor PAR1, Orphan nuclear receptor PXR, PAR, PAR1, PAR2, PARq, Prege X receptor, PRR, PXR, SAR, SXR|
|18171, 84385, 8856|
|Immunoprecipitation, Western Blot|
|PXR Fusion Protein Ag7991|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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