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PXR Rabbit anti-Human, Unconjugated, Polyclonal, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer:  Active MotifSupplier Diversity Partner 39590

Encompass

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Catalog No. 50-199-2728


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Description

Description

This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.
Specifications

Specifications

PXR
Western Blot
Unconjugated
NR1I2
Liquid
Rabbit
IgG
10 μL
-20°C, Avoid Freeze/Thaw Cycles
Primary
8856
NR1I2
Lot-Specific
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
O75469
BXR; mPXR; NR1I2; Nuclear receptor subfamily 1 group I member 2; nuclear receptor subfamily 1, group 1, member 2; nuclear receptor subfamily 1, group I, member 2; ONR 1; ONR1; Orphan nuclear receptor PAR1; Orphan nuclear receptor PXR; PAR; PAR 1; PAR 2; PAR q; PAR1; PAR2; PARq; pregnane X nuclear receptor variant 2; Pregnane X receptor; pregnane X receptor (nuclear receptor sub family 1, group I, member 2); PRR; Pxr; PXR.1; PXR.2; PXR1; SAR; Steroid and xenobiotic receptor; SXR
This PXR antibody was raised against a peptide containing amino acid residues 57-71 of human PXR.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
SDS
Documents
Product Certifications
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