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Pyruvate Carboxylase Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550101

Catalog No. PA550101


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Description

Description

The antibody detects endogenous levels of total Pyruvate Carboxylase protein.

Pyruvate Carboxylase requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency.
Specifications

Specifications

Pyruvate Carboxylase
Polyclonal
Unconjugated
PC
Liquid
PC
Synthesized peptide derived from internal of human PC.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
P11498, Q05920
EC 6.4.1.1, PCB, PYC, Pyruvate carboxylase, mitochondrial
Rabbit
IgG
100 μL
-20°C
Primary
18517, 5091
Documents
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