PYY Monoclonal Antibody (1), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific ABS0290102

Catalog No. 01-670-112

Description

ABS 029-01-02 detects PYY in human samples. ABS 029-01-02 has been successfully used in ELISA and immunohistochemistry procedures NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL

Peptide tyrosine-tyrosine amide (3-36), or PYY (3-36), is a major metabolite of the gut hormone PYY and is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation. PYY (3-36) is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thus disinhibiting anorexigenic POMC neurons. The anorexigenic effect of PYY (3-36) is additive to that of the co-secreted gut hormone GLP-1.

Specifications

• Antigen: PYY
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 15mM sodium azide; pH 7.4
• Gene Accession No.: P10082
• Gene Symbols: Pyy
• Immunogen: Synthetic peptide made to human PYY.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA, Immunohistochemistry (Paraffin)
• Clone: 1
• Conjugate: Unconjugated
• Gene: Pyy
• Gene Alias: GHYY; Peptide tyrosine tyrosine; peptide tyrosine-tyrosine (YY); peptide YY; peptide YY (mapped); Peptide YY(3-36); Peptide YY3-36; Peptide YY3-37; peptide-YY; prepro-PYY; PYY; PYY II; PYY1; PYY-1; PYY-2; PYYI; PYY-I; PYYII; PYY-II; RATGHYY; Yy
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 5697
• Content And Storage: 4° C, store in dark
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov