PYY Polyclonal Antibody, Biotin, Invitrogen™

Chicken Polyclonal Antibody

Supplier:  Thermo Scientific PA19590

Catalog No. 01-674-464

Description

PA1-9590 detects PYY in human, mouse and rat samples. PA1-9590 has been successfully used in ELISA procedures. PA1-9590 immunogen is a synthetic peptide corresponding to amino acids 3-18 (I K P E A P G E D A S P E E L N) of human PYY.

Peptide tyrosine-tyrosine amide (3-36), or PYY (3-36), is a major metabolite of the gut hormone PYY and is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation. PYY (3-36) is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thus disinhibiting anorexigenic POMC neurons. The anorexigenic effect of PYY (3-36) is additive to that of the co-secreted gut hormone GLP-1.

Specifications

• Antigen: PYY
• Classification: Polyclonal
• Conjugate: Biotin
• Gene: Pyy
• Gene Alias: GHYY; Peptide tyrosine tyrosine; peptide tyrosine-tyrosine (YY); peptide YY; peptide YY (mapped); Peptide YY(3-36); Peptide YY3-36; Peptide YY3-37; peptide-YY; prepro-PYY; PYY; PYY II; PYY1; PYY-1; PYY-2; PYYI; PYY-I; PYYII; PYY-II; RATGHYY; Yy
• Host Species: Chicken
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 217212, 287730, 5697
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P10082, P10631, Q9EPS2
• Gene Symbols: Pyy
• Immunogen: Synthetic peptide corresponding to amino acids 3-18 of human PYY.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgY

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov