Tocris R 59-022
Diacylglycerol kinase inhibitor; increases PKC activity
Manufacturer: Tocris 2194/50
DescriptionDiacylglycerol (DAG) kinase inhibitor (IC50 = 2.8µM); increases protein kinase C activity. Potentiates thrombin-induced platelet aggregation and induces neutrophil chemotaxis. Inhibits U46619-induced contractions in mouse aorta and porcine coronary artery.
- Chemical Name: 6-[2-[4-[(4-Fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one
- Formula: C27H26FN3OS
- CAS Number: 93076-89-2
- Solubility: Soluble to 20mM in ethanol and to 50mM in DMSO
- Purity: >98
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