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Tocris™ R 59-022

Diacylglycerol kinase inhibitor; increases PKC activity

Manufacturer:  Tocris™ 2194/50

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Catalog No. 21-945-0

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For Research Use Only



Diacylglycerol (DAG) kinase inhibitor (IC50 = 2.8µM); increases protein kinase C activity. Potentiates thrombin-induced platelet aggregation and induces neutrophil chemotaxis. Inhibits U46619-induced contractions in mouse aorta and porcine coronary artery.
  • Chemical Name: 6-[2-[4-[(4-Fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one
  • Formula: C27H26FN3OS
  • CAS Number: 93076-89-2
  • Solubility: Soluble to 20mM in ethanol and to 50mM in DMSO
  • Purity: >98
Description & Specifications


R 59-022
R 59-022
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