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Tocris Bioscience™ ETP 45658
Potent PI 3-kinase inhibitor; also inhibits DNA-PK and mTOR
Manufacturer: Tocris Bioscience™ 4702/10
Description
PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively). Also inhibits DNA-PK and mTOR (IC50 values are 70.6 and 152 nM respectively). Inhibits proliferation of multiple cancer cell lines in vitro and reduces Akt phosphorylation levels in vivo.This product(s) resides on a Fisher Scientific GSA or VA contract. If you are viewing this page as a nonregistered user, the price(s) displayed is List Price. To view your GSA or VA contract pricing, log in using your account number, or become a registered user by contacting one of our Customer Service teams. You can also view your contract price by searching for this item(s) on GSA Advantage. To place an order, contact Fisher Scientific Customer Service.
Specifications
ETP 45658 | |
C16H17N5O2 | |
3-[1-Methyl-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-6-ylphenol | |
Soluble to 100mM in DMSO | |
Bioactive Small Molecules |
1198357-79-7 | |
311.34 | |
10mg | |
Solid | |
>98% |
Safety and Handling
Recommended Storage : Store at +4°C.
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Research Use Only. Not For Human or Veterinary Use