Tocris Bioscience™ ETP 45658
Potent PI 3-kinase inhibitor; also inhibits DNA-PK and mTOR
Manufacturer: Tocris Bioscience™ 4702/10
DescriptionPI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively). Also inhibits DNA-PK and mTOR (IC50 values are 70.6 and 152 nM respectively). Inhibits proliferation of multiple cancer cell lines in vitro and reduces Akt phosphorylation levels in vivo.
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|Soluble to 100mM in DMSO|
|Bioactive Small Molecules|
Safety and Handling
Recommended Storage : Store at +4°C.
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Research Use Only. Not For Human or Veterinary Use