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Tocris Bioscience ETP 45658
Potent PI 3-kinase inhibitor; also inhibits DNA-PK and mTOR
Manufacturer: Tocris Bioscience 4702/50
This item is not returnable.
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Description
PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively). Also inhibits DNA-PK and mTOR (IC50 values are 70.6 and 152 nM respectively). Inhibits proliferation of multiple cancer cell lines in vitro and reduces Akt phosphorylation levels in vivo.Specifications
ETP 45658 | |
1198357-79-7 | |
311.34 | |
50mg | |
Solid |
>98% | |
C16H17N5O2 | |
3-[1-Methyl-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-6-ylphenol | |
Soluble to 100mM in DMSO | |
Bioactive Small Molecules |
Safety and Handling
Recommended Storage : Store at +4°C.
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Product Title
Research Use Only. Not For Human or Veterinary Use