Tocris Bioscience™ ETP 45658
Potent PI 3-kinase inhibitor; also inhibits DNA-PK and mTOR
Manufacturer: Tocris Bioscience™ 4702/50
DescriptionETP 45658 is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively). Also inhibits DNA-PK and mTOR (IC50 values are 70.6 and 152 nM respectively). Inhibits proliferation of multiple cancer cell lines in vitro and reduces Akt phosphorylation levels in vivo.
|Bioactive Small Molecule|
|Soluble to 100mM in DMSO|
Safety and Handling
Recommended Storage : Store at 4°C
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok
Research Use Only. Not For Human or Veterinary Use