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R&D Systems™ HT Homogeneous PARG Chemiluminescent Inhibition Assay

A highly sensitive high-throughput chemiluminescence screening assay for PARG inhibitors in vitro

Manufacturer:  R&D Systems™ 4691096K

Catalog No. 4691096K

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Includes: 100mU/uL, 50uL; 10x PARG Dilution Buffer, 1mL; D-Luciferin, 900uL; Luciferase Cycling Enzymes, 600uL; 10x dCTP, 900uL; PARG Substrate, 600uL; Cycling Buffer, 6mL; 96-Well White Round Bottom Plate
This item is not returnable. View return policy

Description

Description

Poly(ADP-ribose) glycohydrolase (PARG) is a DNA repair protein which regulates the length of poly(ADP-ribose) (PAR) polymers synthesized by poly(ADP-ribose) polymerase (PARP) during the repair of DNA single-strand
breaks. Knockdown studies have shown that

This end point assay is performed in one step for rapid, easy use
Luciferase cleaves ATP into AMP in the presence of the substrate luciferin, generating a quantifiable light signal
AMP reenters the cycling reaction assay to sustain the light signal for

Specifications

Specifications

96 Tests
Documents
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