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R&D Systems™ Human Biglycan Recombinant Protein Available on GSA/VA Contract for Federal Government customers only.

Manufacturer:  R&D Systems™ 2667CM050

Catalog No. 2667CM050

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Measured by its ability to inhibit the cell growth of mouse 3T3-L1 mouse embryonic fibroblast adipose-like cells. Ward, M. and Ajuwon, K.M. (2011) Cell Proliferation 44:343. The ED 50 for this effect is 1.5-6 µg/mL. Measured by its ability to increase the binding of BMP-4 to Chordin. Moreno, M. et al. (2005) EMBO J. 24:1397. 2-8 µg/mL of Recombinant Human Biglycan will have a 50% maximum increase in the binding of recombinant human BMP-4 (0.1 µg/mL) to recombinant mouse Chordin (1 µg/mL).

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Lyophilized from a 0.2μm filtered solution in PBS.
38 kDa
95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
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