R&D Systems™ Recombinant Human GITR/TNFRSF18 Fc Chimera Protein

Extensive quality control produces lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Supplier:  R&D Systems™ 689GR100

Catalog No. 689GR100

Description

Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human (rh) GITR/TNFRSF18 Fc Chimera at 2 μg/mL (100 μL/well) can bind rhGITR Ligand with a linear range of 0.3-20 ng/mL.

Specifications

• Accession Number: Q9Y5U5
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Molecular Weight (g/mol): M.W. (Observed): 50 kDa, reducing conditions; M.W. (theoretical): 41 kDa (monomer)
• Quantity: 100 μg
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Conjugate: Unconjugated
• Reconstitution: Reconstitute at 100 μg/mL in sterile PBS.
• Protein: GITR/TNFRSF18

• For Use With (Application): Binding Activity
• Gene ID (Entrez): 8784
• Name: GITR/TNFRSF18 Fc Chimera
• Source: Mouse myeloma cell line, NS0-derived human GITR/TNFRSF18 protein Human GITR (Gln26-Glu161) (Thr45Ala) (N-terminus) Accession # Q9Y5U5 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Structural Form: Disulfide-linked homodimer
• Gene Symbol: TNFRSF18
• Recombinant: Recombinant
• Purity or Quality Grade: >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.