R&D Systems™ Recombinant Human PD-1 Fc Chimera Protein, CF
Extensive quality control produces lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Binding Activity
Manufacturer: R&D Systems™ 1086PD050
DescriptionMeasured by its binding ability in a functional ELISA. When Recombinant Human PD-1 Fc Chimera is immobilized at 0.1 μg/mL (100 μL/well), Recombinant Human B7-H1/PD-L1 Fc Chimera (Catalog # 156-B7 ) binds with a typical ED50 of 0.15-0.75 μg/mL.
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|CD279, CD279 antigen, hPD-1, PD1, PD1hPD-l, PDCD1, programmed cell death 1, programmed cell death protein 1, Protein PD-1, SLEB2|
|>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.|
|Mouse myeloma cell line, NS0-derived human PD-1 protein Human PD-1 (Leu25-Gln167) (N-terminus) Accession # Q15116 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)|
|<0.01 EU / 1 µg of the protein by the LAL method.|
|Lyophilized from a 0.2 µm filtered solution in PBS.|
|M.W. (Observed): 60-70 kDa, reducing conditions; M.W. (theoretical): 42.6 kDa (monomer)|
|Reconstitute at 0.5 mg/mL in sterile PBS.|
|Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.|
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