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R&D Systems™ Recombinant Human TIM-3 Fc Chimera Protein
Extensive quality control produces lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Binding Activity
Supplier: R&D Systems™ 2365TM050
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Description
Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human Galectin-9 (Catalog # 2045-GA ) at 500 ng/mL can bind Recombinant Human TIM-3 Fc Chimera with an apparent Kd <30 nM.Specifications
Q8TDQ0 | |
Lyophilized from a 0.2 μm filtered solution in PBS. | |
M.W. (Observed): 66 kDa, reducing conditions; M.W. (theoretical): 46.4 kDa (monomer) | |
50 μg | |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 3 months, -20°C to -70°C under sterile conditions after reconstitution. | |
<0.10 EU / 1 μg of the protein by the LAL method. | |
HAVCR2 | |
Recombinant | |
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining. |
Binding Activity | |
84868 | |
TIM-3 Fc Chimera | |
Mouse myeloma cell line, NS0-derived human TIM-3 protein Human TIM-3 (Ser22-Arg200) (N-terminus) Accession # Q8TDQ0 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus) | |
Disulfide-linked homodimer | |
CD366, FLJ14428, HAVcr-2, HAVCR2, hepatitis A virus cellular receptor 2, kidney injury molecule-3, KIM-3, SPTCL, T cell immunoglobulin mucin 3, T cell immunoglobulin mucin-3, T-cell immunoglobulin and mucin domain-containing protein 3, TIM 3, Tim-3, TIM3, TIM3 T-cell membrane protein 3, TIMD3, TIMD-3, TIMD3KIM-3 | |
Unconjugated | |
Reconstitute at 100 μg/mL in sterile PBS. | |
TIM-3 |
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