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Tocris Bioscience™ IHR 1
Potent Smo antagonist
Supplier: Tocris Bioscience™ 5554/50
Description
IHR 1 is a potent Smo antagonist (IC50 = 7.6 nM). Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro.Fluorescent Analog also available.
Specifications
IHR 1 | |
N,N'-1,4-Phenylenebis[2,5-dichlorobenzamide] | |
Soluble to 20mM in DMSO with gentle warming | |
454.13 | |
Bioactive Small Molecule |
548779-60-8 | |
50 mg | |
C20H12Cl4N2O2 | |
Solid | |
>99% |
Safety and Handling
Recommended Storage : Store at 4°C
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Research Use Only. Not For Human or Veterinary Use