R&D Systems Maritoclax, Tocris
Mcl-1 inhibitor; disrupts Mcl-1-Bim interaction and induces Mcl-1 proteasomal degradation
Manufacturer: R&D Systems 5368/10
- Exhibits no effect on Bcl-XL-Bim interaction
- Selectively induces apoptosis in Mcl-1-dependent K562 leukemia cells
- Sensitizes K562 and Raji cells to ABT-737-induced apoptosis
|Soluble to 100mM in DMSO and to 50mM in ethanol|
|Bioactive Small Molecules|
Safety and Handling
Recommended Storage : Store at -20°C.
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