R&D Systems MRS 1477, Tocris™

TRPV1 positive allosteric modulator

Manufacturer: R&D Systems 5246/50

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Catalog No. 524650

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Disclaimers:

Research Use Only. Not For Human or Veterinary Use


    Specifications

    Chemical Name or Material MRS 1477
    CAS 212200-21-0
    Assay Percent Range >98%
    Molecular Formula C21H27NO4S
    Formula Weight 389.51
    Synonym 4-Ethyl-1,4-dihydro-5-[[(2-methoxyethyl)thio]carbonyl]-6-methyl-2-phenyl-3-pyridinecarboxylic acid ethyl ester
    Recommended Storage Store at -20°C.
    Quantity 50mg
    Solubility Soluble to 100mM in DMSO and to 50mM in ethanol
    Physical Form Solid
    Product Type Bioactive Small Molecules

    • Potentiates vanilloid and proton activation of TRPV1 channels
    • Exhibits analgesic effects in combination with capsaicin in rats
    • Also prolongs capsaicin-induced hypothermia in mice

  • Description & Specifications

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