R&D Systems MRS 1477, Tocris™

TRPV1 positive allosteric modulator

Manufacturer: R&D Systems 5246/10

 View more versions of this product

Catalog No. 524610

  Check Availability
Add to Cart


Research Use Only. Not For Human or Veterinary Use


    Chemical Name or Material MRS 1477
    CAS 212200-21-0
    Assay Percent Range >98%
    Molecular Formula C21H27NO4S
    Formula Weight 389.51
    Synonym 4-Ethyl-1,4-dihydro-5-[[(2-methoxyethyl)thio]carbonyl]-6-methyl-2-phenyl-3-pyridinecarboxylic acid ethyl ester
    Recommended Storage Store at -20°C.
    Quantity 10mg
    Solubility Soluble to 100mM in DMSO and to 50mM in ethanol
    Physical Form Solid
    Product Type Bioactive Small Molecules

    • Potentiates vanilloid and proton activation of TRPV1 channels
    • Exhibits analgesic effects in combination with capsaicin in rats
    • Also prolongs capsaicin-induced hypothermia in mice

  • Description & Specifications

Related Products

Product Content Feedback

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit