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Tocris Bioscience™ NS 8593 Hydrochloride

Selective negative modulator of KCa2 (SK) channels; inhibits SK currents

Specifications

Product Type Bioactive Small Molecule
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
459710
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Tocris Bioscience™
4597/10
10 mg N/A
459750
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Tocris Bioscience™
4597/50
50 mg N/A
Description

Description

Selective KCa2 (SK) channel negative modulator; inhibits SK channel currents (Kd values are 0.42, 0.6 and 0.73 μM for SK1, SK2 and SK3 respectively at 0.5 μM Ca2+). Exhibits selectivity for SK channels over KCa1.1 (BK), KCa3.1 (IK), Kv, Nav and Cav channels. Inhibits afterhyperpolarization in hippocampal slices.
Specifications

Specifications

Bioactive Small Molecule
Safety and Handling

Safety and Handling

Recommended Storage : Store at 4°C

SDS
Product Certifications

Research Use Only. Not For Human or Veterinary Use

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