R&D Systems PARP Enzyme High Specific Activity

Purified from E. coli containing a recombinant plasmid harboring the human PARP gene

Manufacturer: R&D Systems 4668-500-01

 View more versions of this product

Catalog No. 466850001

  Check Availability
Add to Cart

    Specifications

    Product Name Poly [ADP-ribose] Polymerase Enzyme High Specific Activity
    Quantity 500μL

    PARP [Poly(ADP-ribose) Polymerase], also known as ADPRT and PPOL, is a 118kDa enzyme that uses NAD as a substrate to catalyze the covalent transfer of ADP-ribose to a variety of nuclear protein acceptors. ADP ribosyltransferase is required for cellular repair, and PARP expression is induced by single-strand breaks in DNA. PARP is proteolytically cleaved by Caspase-3 into two fragments of 89 and 24kDa in one of the hallmark events of apoptosis.

    • One unit of PARP incorporates 10femtomoles of NAD onto immobilized histones in 30 minutes
    • High specific activity PARP is provided at 10 units/µL

  • Description & Specifications

Related Products


Product Content Feedback

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit