Learn More
R&D Systems PARP Enzyme High Specific Activity
Purified from E. coli containing a recombinant plasmid harboring the human PARP gene
Manufacturer: R&D Systems 466810001
Description
PARP [Poly(ADP-ribose) Polymerase], also known as ADPRT and PPOL, is a 118kDa enzyme that uses NAD as a substrate to catalyze the covalent transfer of ADP-ribose to a variety of nuclear protein acceptors. ADP ribosyltransferase is required for cellular repair, and PARP expression is induced by single-strand breaks in DNA. PARP is proteolytically cleaved by Caspase-3 into two fragments of 89 and 24kDa in one of the hallmark events of apoptosis.
- One unit of PARP incorporates 10femtomoles of NAD onto immobilized histones in 30 minutes
- High specific activity PARP is provided at 10 units/µL
Specifications
Poly [ADP-ribose] Polymerase Enzyme High Specific Activity | |
100μL | |
Store at -20° C in a manual defrost freezer. For long-term storage, freeze in working aliquots at -80° C. Avoid freeze-thaw cycles. |
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.