Tocris Bioscience™ PFI 4
Potent and selective BRPF1 bromodomain inhibitor
Manufacturer: Tocris Bioscience™ 5576/10
DescriptionPFI 4 is a potent and selective BRPF1B bromodomain inhibitor (IC50 = 172 nM). Exhibits >100-fold selectivity for BRPF1 over a panel of other bromodomains including BRPF2 (BRD1), BRPF3 and BRD4. Disrupts BRPF1 binding to histone H3.3. Cell permeable. Inhibits osteoclastogenesis.
|Bioactive Small Molecule|
|Soluble to 50mM in DMSO and to 10mM in ethanol|
Safety and Handling
Recommended Storage : Store at 4°C
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Research Use Only. Not For Human or Veterinary Use