Interferon-beta (IFN-beta), along with IFN-alpha and IFN-omega, is a member of the type I interferon family. All three type I interferons share a common cell surface receptor that is composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. Type I interferons were originally described as potent anti-viral molecules produced by virally infected cells.
Source: Human embryonic kidney cell, HEK293-derived, Ile22-Asn182 Accession No.: P01575 N-terminal Sequence Analysis: Ile22 Structure: Monomer Purity: >95%, by SDS-PAGE with silver staining Predicted Molecular Mass: 20 kDa SDS-PAGE: 30-38 kDa, reducing conditions Activity: Measured in an anti-viral assay using LG929 mouse fibroblast cells infected with encephalomyocarditis (EMC) virus
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