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Tocris Bioscience™ XD 14

BET bromodomain inhibitor


Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
548910 View Documents Tocris Bioscience™
5489/10
This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
548950 View Documents Tocris Bioscience™
5489/50
This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

BET bromodomain inhibitor (Kd values are 160, 170, 380, 490, 830 and 850 nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2) respectively). Also inhibits BRDT(1), CBP, p300 and BRDT(2) (Kd values are 1.2, 1.6, 2.6 and 3.7 μM respectively). Attenuates proliferation of HL-60 leukemia cells in vitro.

Research Use Only. Not For Human or Veterinary Use

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