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RAB11A Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 202291AP

Catalog No. 50-173-2781


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Description

Description

The antibody is specific to RAB11A, and has no cross reaction to RAB11B.

Rab11A is a member of the YPT-1 subfamily of Ras-related GTP-binding proteins. Rab11A mRNA has been detected in a variety of tissues including brain, testis, spleen, heart, and gastrointestinal mucosa. In the gastric fundus the Rab11A protein is expressed in parietal cell tubulovesicles membranes. Expression of the Rab11A protein appears to occur in discrete epithelial cell populations where it localizes to apical vesicular populations. Recent studies have shown Rab11A is essential for resecretion of alpha-synuclein out of neuronal cells via endosome recycling and is required for exocytosis of discoidal/fusiform vesicles of bladder umbrella cells. Rab11A is also implicated in biogenesis of Birbeck granules and endosomal activation of the PI3K/AKT signaling pathway via G beta gamma trafficking.
Specifications

Specifications

RAB11A
0.25 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P62491, P62492
Rab 11, RAB11, RAB11A, Ras related protein Rab 11A, YL8
Rabbit
IgG
150 μL
-20°C
Primary
53869, 8766
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
RAB11A
Liquid
Rab11a
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
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