RAB12 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA548179
Predicted to react with rat based on sequence homology.The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy.
|KLH conjugated synthetic peptide between 63-92 amino acids from the N-terminal region of human RAB12.|
|Protein A, Antigen Affinity Chromatography|
|PBS with 0.09% sodium azide|
|Ras-related protein Rab-12, RAB12|
|-20° C, Avoid Freeze/Thaw Cycles|
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