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RAB21 Mouse anti-Human, Non-human primate, Clone: 1701CT536.68.39, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524755

Catalog No. PIMA524755

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

RAB21 is a member of a subfamily of small GTP-binding protein genes of the Ras superfamily that plays an important role in intracellular vesicular targeting. In non-polarized Caco-2 cells, RAB21 showed a general endoplasmic reticulum (ER)-like localization, while in polarized cells, RAB21 localized to apical vesicles. RAB21 has been shown to associate with integrin subunits and to be important for receptor entry into cells via RAB5/RAB21 endosomes. The GTPase-activating protein p120RasGAP regulates cell motility by controlling the return of the endocytosed integrins to the plasma membrane by competing with RAB21 for binding to overlapping sites on the Alpha-tail of endocytosed integrin.
Specifications

Specifications

RAB21
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide
Q9UL25
Ras-related protein Rab-21, RAB21, KIAA0118
Mouse
IgG2b, kappa
200 μL
-20°C
Primary
23011
Western Blot
1701CT536.68.39
Unconjugated
RAB21
Liquid
RAB21
recombit protein between 1-225 amino acids from the human RAB21
Protein G
RUO
Antibody
Monoclonal
Human, Non-human primate
Documents
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