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RAB21 Mouse anti-Canine, Human, Mouse, Non-human primate, Rat, Clone: OTI6E12, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526200

Catalog No. PIMA526200


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Description

Description

RAB21 is a member of a subfamily of small GTP-binding protein genes of the Ras superfamily that plays an important role in intracellular vesicular targeting. In non-polarized Caco-2 cells, RAB21 showed a general endoplasmic reticulum (ER)-like localization, while in polarized cells, RAB21 localized to apical vesicles. RAB21 has been shown to associate with integrin subunits and to be important for receptor entry into cells via RAB5/RAB21 endosomes. The GTPase-activating protein p120RasGAP regulates cell motility by controlling the return of the endocytosed integrins to the plasma membrane by competing with RAB21 for binding to overlapping sites on the Alpha-tail of endocytosed integrin.
Specifications

Specifications

RAB21
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q6AXT5, P35282, Q9UL25, P55745
Ras-related protein Rab-21, RAB21, KIAA0118
Mouse
IgG2b
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
100683312, 216344, 23011, 299799, 718715
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI6E12
Unconjugated
RAB21
Liquid
Rab21
Full length human recombit protein of RAB21 produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Canine, Human, Mouse, Non-human primate, Rat
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