Invitrogen™ RAB29 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550109

Catalog No. PA550109

Description

The antibody detects endogenous levels of total RAB29 protein.

Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans-Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection. {ECO:0000269; PubMed:22042847, ECO:0000269; PubMed:24788816}.

Specifications

• Antigen: RAB29
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAB29
• Gene Alias: RAB29; RAB29, member RAS oncogene family; RAB7, member RAS oncogene family-like 1; RAB7L; RAB7L1; Rab-7-like protein 1; Ras-related GTP-binding protein Rab29; ras-related protein Rab-29; Ras-related protein Rab-7L1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 226422, 8934
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O14966, Q91YQ1
• Gene Symbols: RAB29
• Immunogen: Synthesized peptide derived from internal of human RAB7L1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG