Invitrogen™ RAB33A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA537028

Catalog No. PIPA537028

Description

This antibody detects endogenous protein at a molecular weight of 27 kDa. Purity is >95% by SDS-PAGE.

The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies. Increasing data suggests an important role for Rab proteins in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 33B and Rab 33A share conserved effector domains, but share only 55.3% overall amino acid identity. This suggests that Rab 33B and Rab 33A may interact with similar effector and regulatory proteins.

Specifications

• Antigen: RAB33A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAB33A
• Gene Alias: RAB 33A; Rab33a; RAB33A, member of RAS oncogene family; RAB33A, member RAS oncogene family; Rabs10; Ras-related protein Rab-33A; RGD1563280; small GTP-binding protein S10
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19337, 317580, 9363
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P97950, Q14088
• Gene Symbols: RAB33A
• Immunogen: Synthetic peptide corresponding to amino acids 173-218 of human RAB33A.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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