Invitrogen™ RAB43 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA570752

Catalog No. PIPA570752

Description

RAB43 Polyclonal Antibody for Western Blot

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.

Specifications

• Antigen: RAB43
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAB43
• Gene Alias: 1810048P08Rik; 2500004H21Rik; AW490415; RAB11B; RAB41; Rab43; RAB43, member RAS oncogene family; ras-related protein Rab-41; Ras-related protein Rab-43
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 339122
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q86YS6
• Gene Symbols: RAB43
• Immunogen: synthetic peptide directed towards the C-terminal region of human RAB43.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG