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RAB5A Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 202281AP

Catalog No. 50-173-2780


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Description

Description

The antibody is specific to RAB5A. It has no cross reaction to RAB5B or RAB5C.

RAB5 are among the small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension. Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan. Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3.
Specifications

Specifications

RAB5A
0.22 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P20339, Q9CQD1
RAB5, RAB5A, Ras related protein Rab 5A
Rabbit
IgG
150 μL
-20°C
Primary
271457, 5868
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
RAB5A
Liquid
Rab5a
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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